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SP600125: Unveiling JNK Inhibition for Precision Phosphop...
2025-10-18
Explore how SP600125, a selective JNK inhibitor, is revolutionizing phosphoproteomic studies and signal transduction research. This article provides a unique, in-depth analysis linking ATP-competitive JNK inhibition to advanced kinase-substrate mapping and translational applications.
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Strategic Hsp70 Inhibition with VER 155008: Translational...
2025-10-17
This thought-leadership article explores the mechanistic landscape and translational opportunities enabled by VER 155008 (HSP 70 inhibitor, adenosine-derived), highlighting its role in disrupting Hsp70 chaperone pathways, modulating apoptosis, and interrogating liquid-liquid phase separation phenomena relevant to cancer and neurodegenerative disorders. We synthesize foundational biology, cutting-edge evidence, and strategic guidance to empower advanced researchers.
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